Children's Cancer Research Fund

Children's Cancer Research Fund fuels transformational research to bring better treatments and cures to children with cancer.

This holiday season, your generosity can go twice as far!

Through the Holiday Hope Matching Challenge, Nov. 1–Dec. 31, every gift will be matched up to $125,000, doubling your opportunity to invest in research that can change the future of childhood cancer.

Childhood cancer is a devastating diagnosis—in fact, cancer is the leading cause of death by disease in kids in the U.S. But research can change what comes next. For over 45 years, Children's Cancer Research Fund has awarded more than $235 million to researchers nationwide who are tackling the hardest questions — from cancers with the lowest survival rates to long-term side effects, chronic conditions and health disparities. Because every child, no matter where they live or what cancer they face, deserves access to hope.

Research is saving lives — but it needs our support to keep going.

Today, researchers are asking bold questions, and finding the answers takes sustained funding. Applications to CCRF have increased 132% since 2024, revealing growing demand and critical gaps in childhood cancer research. In the years ahead, CCRF is focused on some of the biggest challenges children with cancer still face: getting ahead of relapse, closing remaining survival gaps and helping more kids live full lives after cancer.

Your generosity will directly determine how many of these promising therapies advance from a proposed idea—to lab—to lifeline for kids with cancer.  

              

Thanks to decades of research, survival rates have improved. But today, 1 in 5 kids diagnosed with cancer in the U.S. still won’t survive. And for those who do, the treatment they receive will leave lifelong physical and emotional scars. 

Your support isn’t extra — it’s essential.

More than half of all childhood cancer research in the U.S. is funded by private donors. And with recent cuts to federal funding, your generosity is more critical than ever. Progress doesn’t just happen in labs — it happens when people like you choose to care. 

You're helping create a future where kids with cancer not only survive — they thrive.